400 million people worldwide suffered from extrapolations of the World Health Organization e census

Is the gut flora to blame for obesity? Some people can eat all the cream pie without being thick. Now it is increasingly clear that in addition to genes, the bacterial community in our body has a big hand in it.
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The trillion bacteria counting intestinal flora of humans apparently decides to a large part in determining whether a person is thick and developed metabolic disorders. Be the diversity of the bacterial community in the gut low, get the probability of obesity and insulin resistance, researchers report in the journal "Nature". Whether e census a person belongs e census to this risk group, let be determined easily. Why the intestinal flora is depleted in about one-quarter of the population in industrialized e census countries, however, still needed to be clarified.
400 million people worldwide suffered from extrapolations of the World Health Organization e census (WHO), 2005 overweight by 2015, it could be more than 700 million. In Switzerland were in 2012 according to a recent analysis of the health survey, e census 41 percent of the population aged 15 years and overweight. Debt are a good part of the genes, such as twin and family studies have shown the team writes to Stanislav Dusko Ehrlich from the French Institute for Agronomic Research (INRA) in Jouy en Josas and Oluf Pedersen of the University of Copenhagen (Denmark) in Nature . But now see more clearly that the influence of the intestinal flora is probably the more significant factor. This is confirmed by genetic analysis of the microbiome - the totality of microbes that colonize humans.
The scientists had studied the intestinal flora of 292 Danes. 123 of them were normal, 169 overweight. The subjects settled in two groups: those eintönigerer with diverse e census bacteria genes and more species-rich flora and those with up to 40 percent of microbial colonization. The latter, about a quarter of the subjects had been more often overweight and suffering from insulin resistance or lipid metabolism disorder (dyslipidemia). e census For them, the probability of future weight gain also was higher. As for the rain forest, as is also true for the intestinal flora: the more diversity the better, the study authors write.
There were enough genetic markers typically present some bacterial species to assign people one of the two groups. In people with diverse flora therefore dominate among other Faecali bifidobacteria and lactobacilli and the bacterial community. Those with less diversity in the digestive tract is about Bacteroides, and Ruminococcus Parabacteroides, the scientists report. It is noticeable in them also the increased occurrence of bacteria that are associated with inflammatory responses of the body.
A correlation between low intestinal microflora and much Bacteroides his team have also been found, says Peer Bork of the European Molecular Biology Laboratory e census (EMBL) in Heidelberg. The results of the "Nature" study were inconclusive, but careful to enjoy their absolute e census numbers. e census The number of subjects was quite small, e census also the diversity of the intestinal flora is in degree, not divided into clearly separated steps. A quarter of the population classified as abnormal, could be much too ambitious. Even short-term effects after about taking antibiotics or occasionally e census of other food were not taken into account.
Ehrlich's e census team monitored in a second study, the intestinal flora 49 overweight or obese people e census during a low-fat diet. The subjects were given six weeks an aligned on losing weight and keeping then a six-week weight diet. It was found that a high fiber-rich diet with plenty of vegetables and fruits let grow the diversity of the intestinal flora. This confirms e census the conclusion of previous studies which showed that the diet of the microbiome affects - and let hope that the intestinal flora can have a lasting change towards more diversity.
The study results provide a possible e census explanation for why many people did not suffer from cardiovascular disease or diabetes despite being overweight, write Sungsoon Fang and Ronald Evans of the Salk Institute for Biological Studies in La Jolla (California, USA) in an accompanying e census text in " Nature ". This could be because they belonged to the group with a variety of intestinal flora. Still needed to clarify whether the variety is only the health of the metabolism reflects - or whether it is possible retarding influence on certain diseases of the variability of the intestinal flora.
In principle, the results confirmed ancient wisdom about healthy diets,